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CD2AP — EGF

Text-mined interactions from Literome

Schiffer et al., J Biol Chem 2004 : CD2AP was not required for PI3K/AKT activation by insulin and epidermal growth factor , indicating that CD2AP is a selective mediator of anti-apoptotic TGF-beta signaling
Lu et al., Gene 2009 : In this study, we showed that epidermal growth factor (EGF) led to an increase of the CD2AP protein and mRNA in the human renal proximal tubular epithelial cell line HK-2 cells, which was due to the elevation of CD2AP promoter activity ... Furthermore, EGF induced increases of CD2AP protein and mRNA expressions in HK-2 cells were significantly inhibited by the transfection of dominant negative JunD or c-fos vector, which was in parallel with a marked reduction of antiapoptotic effect of EGF