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CCND1 — EIF2AK2

Text-mined interactions from Literome

Campo et al., Cell Growth Differ 2002 : 15d-PGJ ( 2 ) strongly stimulates eIF-2alpha phosphorylation and down-regulates cyclin D1 expression in a cell line derived from wild-type mouse embryo fibroblasts but has an attenuated effect in PKR-null cells, providing evidence that PKR is involved in mediating the effect of 15d-PGJ ( 2 ) on eIF-2alpha phosphorylation and cyclin D1 expression
Raven et al., J Biol Chem 2008 : PKR and PKR-like endoplasmic reticulum kinase induce the proteasome dependent degradation of cyclin D1 via a mechanism requiring eukaryotic initiation factor 2alpha phosphorylation
Raven et al., Cell cycle (Georgetown, Tex.) 2008 : Specifically, we demonstrated that degradation of the cell cycle regulator cyclin D1 , and the tumour suppressor p53 was promoted by PERK and PKR during periods of ER stress