Gene interactions and pathways from curated databases and text-mining

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IL6 — TRAF2

Text-mined interactions from Literome

Baccam et al., Eur J Immunol 1999 : Thus, CD40 mediated IL-6 induction is independent of NF-kappaB activation and the binding of TRAF2 and -3, but CD40 must be engaged by trimeric CD154 on cell membranes to activate production of IL-6
Horie et al., Microbes Infect 2007 (HIV Infections) : TRAF activation of C/EBPbeta ( NF-IL6 ) via p38 MAPK induces HIV-1 gene expression in monocytes/macrophages
Zhu et al., Cytokine 2010 (Glomerulonephritis...) : Knockdown TRAF-2 by siRNA significantly suppressed soluble AIgG induced up-regulation of TRAF-2, IL-1beta, and IL-6