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CREBBP — NOTCH1
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
CREBBP
→
NOTCH1
(reaction)
Fryer et al., Genes Dev 2002, Wallberg et al., Mol Cell Biol 2002, Fryer et al., Mol Cell 2004, Nam et al., Cell 2006
-
Reactome Reaction:
CREBBP
→
NOTCH1
(indirect_complex)
Fryer et al., Genes Dev 2002, Wallberg et al., Mol Cell Biol 2002, Nam et al., Cell 2006
-
Reactome Reaction:
CREBBP
→
NOTCH1
(direct_complex)
Text-mined interactions from Literome
Chen et al., Basic Clin Pharmacol Toxicol 2007
(Leukemia) :
Curcumin, both histone deacetylase and
p300/CBP-specific inhibitor,
represses the activity of nuclear factor kappa B and
Notch 1 in Raji cells
Fu et al., J Biol Chem 2009
:
This is the first evidence that
Notch activation
affects R-Smad expression and that cooperative induction of histone acetylation at specific promoters underlies the selective synergy between Notch and TGFbeta signaling pathways