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CDKN1A — LPA

Text-mined interactions from Literome

Kim et al., Arch Pharm Res 2003 (MAP Kinase Signaling System) : LPA decreased cyclin D1 and cyclin D2 levels but increased p21 ( WAF1/CIP1 ) ( p21 ) and p27KIP1 ( p27 ) levels, which are known inhibitors of cyclin dependent kinase
Wu et al., Mol Cancer Res 2011 (Breast Neoplasms...) : We examined the possibility that LPA induced p21 might contribute to the cytostatic response to TGFß ... LPA stimulated p21 via LPA ( 1 ) and LPA ( 2 ) receptors and Erk dependent activation of the CCAAT/enhancer binding protein beta transcription factor independent of p53
Kanehira et al., PloS one 2012 : Expressions of p16(Ink4a), Rb, p53, and p21 ( Cip1 ), which have been associated with cellular senescence, were all reduced in human MSCs by the pharmacological inhibition of LPA signaling
Iwabayashi et al., Biochem Biophys Res Commun 2012 (Atherosclerosis...) : On the other hand, HGF significantly attenuated EPC dysfunction, senescence, ROS production, and p53 and p21 expression induced by Lp(a)