Gene interactions and pathways from curated databases and text-mining

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GHSR — LEP

Text-mined interactions from Literome

Nogueiras et al., Diabetes 2004 (Diabetes Mellitus...) : These results show that the level of GHS-R expression in the ARC is reduced by leptin and increased by ghrelin and that the effect of ghrelin may be GH dependent
Perello et al., J Comp Neurol 2012 (Body Weight...) : Thus, we conclude that ghrelin and leptin act largely on distinct neuronal populations and that ghrelin receptor deficiency does not affect sensitivity to the anorexigenic and body weight lowering actions of leptin
Van den Berghe et al., J Clin Endocrinol Metab 1998 (Critical Illness) : In contrast, GH-secretagogues elevated leptin levels within 12 h. Infusion of GHRP-2 alone induced a maximal leptin increase of +87 % after 24 h, whereas GHRH + GHRP-2 elevated leptin by up to +157 % after 24 h