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IRF6 — TNFRSF1B
Text-mined interactions from Literome
Fairfax et al., J Immunol 2011
:
Functional studies demonstrate a positive-feedback loop via TNFR2 of LPS induced TNF release, confirming this previously unrecognized
role for
TNFR2 in the modulation of
LPS response
Lopatnikova et al., J Recept Signal Transduct Res 2013
:
We also established that stimulation of peripheral blood mononuclear cells ( PBMCs ) with the
lipopolysaccharide (LPS) significantly
increased the number of TNFRI and
TNFRII on CD14 ( + ) monocytes
Manthey et al., Infect Immun 1993
:
Herein, we examined the ability of these structures to
regulate murine macrophage tumor necrosis factor (TNF) secretion and
LPS-inducible gene expression ( tumor necrosis factor alpha [TNF-alpha ], interleukin-1 beta [IL-1 beta ], IP-10, type 2 TNF receptor
[TNFR-2 ], D3, and D8 genes ) ...
Induction of
TNFR-2 by
LPS was relatively resistant to inhibition by RsDPLA, and induction of TNFR-2 and D3 was relatively resistant to inhibition by SDZ 880.431
Dickensheets et al., Blood 1997
:
LPS stimulation
induced rapid, but transient loss ( shedding ) of mTNF-RII molecules and a delayed, but marked increase in
TNF-RII mRNA levels