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IL2 — SPN

Text-mined interactions from Literome

Santana et al., J Biol Chem 2000 : In this study we show that CD43 ligation on human normal peripheral T cells was sufficient to induce interleukin-2 , CD69, and CD40-L gene expression, without requiring signals provided by additional receptor molecules
Tong et al., J Exp Med 2004 : Thus, the exclusion of the CD43 intracellular region from the immunological synapse is required for CD43 regulation of interleukin-2 production, but the presence of the cytoplasmic tail, independent of its location, is sufficient to reverse CD43 ( -/- ) T cell hyperproliferation
Velten et al., Mol Immunol 2007 : CD25 ( high ) DC ( ims ) showed significant up-regulation of the DC activation molecule CD43 and induced increased levels of IL-2 secretion in allogeneic T-cells ( 170.7+/-86.7pg/mL ) as compared to T-cells coincubated with CD25 ( low ) DC ( ims ) ( 86.6+/-37.6pg/mL ) [ p=0.0224 ]
Pedraza-Alva et al., J Biol Chem 1998 : Altogether, these data suggest that the mitogen activated protein kinase pathway is involved in CD43 dependent interleukin-2 gene expression