Gene interactions and pathways from curated databases and text-mining

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IL2 — PRR4

Text-mined interactions from Literome

Kim et al., EMBO J 2002 : Lineage restricted and activation dependent IL-2Ralpha transcription is controlled by four upstream positive regulatory regions ( PRRs ) and one downstream PRR
Zubcevic et al., Hypertension 2013 (Hypertension) : Finally, PRR activation in SHR neuronal cultures by prorenin activated nuclear factor-?B and increased mRNA levels of interleukin-1ß ( 250-fold ), tumor necrosis factor-a ( 32-fold ), interleukin-6 ( 35-fold ), C-C motif ligand 5 ( 12-fold ), and interleukin-10 ( 7-fold ) in a nuclear factor-?B dependent but angiotensin II type 1 receptor independent manner