◀ Back to CD79B
CD79B — FCGR2B
Pathways - manually collected, often from reviews:
-
NCI Pathway Database BCR signaling pathway:
RasGAP (RASA1)
→
B-cell antigen/BCR complex/FcgammaRIIB complex (FCGR2B-CD79B-CD79A)
(modification, collaborate)
-
NCI Pathway Database BCR signaling pathway:
Csk (CSK)
→
B-cell antigen/BCR complex/FcgammaRIIB complex (FCGR2B-CD79B-CD79A)
(modification, collaborate)
-
NCI Pathway Database BCR signaling pathway:
RasGAP (RASA1)
→
B-cell antigen/BCR complex/FcgammaRIIB complex (FCGR2B-CD79B-CD79A)
(modification, collaborate)
Tamir et al., Immunity 2000
-
NCI Pathway Database BCR signaling pathway:
p62DOK (DOK1)
→
B-cell antigen/BCR complex/FcgammaRIIB complex (FCGR2B-CD79B-CD79A)
(modification, collaborate)
Tamir et al., Immunity 2000
-
NCI Pathway Database BCR signaling pathway:
SHIP (INPP5D)
→
B-cell antigen/BCR complex/FcgammaRIIB complex (FCGR2B-CD79B-CD79A)
(modification, collaborate)
Tamir et al., Immunity 2000
-
NCI Pathway Database BCR signaling pathway:
B-cell antigen/BCR complex complex (CD79B-CD79A)
→
FcgammaRIIB (FCGR2B)
(modification, collaborate)
Vuica et al., J Exp Med 1997*
Evidence: assay, other species
-
NCI Pathway Database BCR signaling pathway:
B-cell antigen/BCR complex complex (CD79B-CD79A)
→
B-cell antigen/BCR complex/FcgammaRIIB complex (FCGR2B-CD79B-CD79A)
(modification, collaborate)
Vuica et al., J Exp Med 1997*
Evidence: assay, other species
-
NCI Pathway Database BCR signaling pathway:
FcgammaRIIB (FCGR2B)
→
B-cell antigen/BCR complex/FcgammaRIIB complex (FCGR2B-CD79B-CD79A)
(modification, collaborate)
Vuica et al., J Exp Med 1997*
Evidence: assay, other species
Text-mined interactions from Literome
Sohn et al., J Immunol 2008
:
That lipid rafts play a role in
FcgammaRIIB 's
regulation of
BCR signaling was suggested by recent studies showing that a lupus associated loss of function mutation resulted in the receptor 's exclusion from lipid rafts and the failure to regulate BCR signaling
Wang et al., J Exp Med 1996
:
Compared with control B cells, Lyn-/- B cells were hyper responsive to anti-IgM induced proliferation and defective in
Fc gamma RIIB mediated suppression of
B cell antigen receptor (BCR) signaling, indicating that Lyn is involved in the negative regulation of BCR signaling