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BCL10 — INS
Text-mined interactions from Literome
Iida et al., Arterioscler Thromb Vasc Biol 2002
:
In the exploration of the signaling pathway involved in these antiapoptotic effects of insulin, pretreatment of cells with a specific inhibitor of phosphatidylinositol-3-kinase significantly suppressed insulin mediated cell survival and
insulin induced
Bcl-XL expression in macrophages
Augustin et al., Reproduction 2003
:
No
effects of
insulin on the mRNA expression of Glut isoforms and Bax and
Bcl-XL were found
Swaminathan et al., J Cell Physiol 2006
(Cell Transformation, Neoplastic) :
In addition, it addresses the functional requirements for E3
Ubiquitin ligase activity of Cbl and negative
regulation of Cbl mediated downregulation of PTKs, ( b ) Adaptor functions : This section discusses the mechanisms of adaptor functions of Cbl in mitogen activated protein kinase ( MAPK ) activation,
insulin signaling, regulation of Ras related protein 1 (Rap1), PI-3 ' kinase signaling, and regulation of Rho-family GTPases and cytoskeleton ; Biological functions : This section gives an account of the diverse biological functions of Cbl and includes the role of Cbl in transformation, T-cell signaling and thymus development, B-cell signaling, mast-cell degranulation, macrophage functions, bone development, neurite growth, platelet activation, muscle degeneration, and bacterial invasion ; Conclusions and perspectives
Navarro et al., Exp Cell Res 1998
:
Moreover,
insulin down-regulated
Bcl-xS expression without inducing the expression of Bcl-xL