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ICAM1 — STAT3

Text-mined interactions from Literome

Wooten et al., J Biol Chem 2000 : Activation of Stat3 leads to homotypic cell aggregation, increased expression of intercellular adhesion molecule 1 ( ICAM-1 ), CD18, and CD11b, and activation of signaling through CD18 containing integrins
Chang et al., Mol Pharmacol 2004 : ICAM-1 promoter activities induced by the overexpression of wild-type JAK1- and PLC-gamma2 were blocked by the PLCgamma2 mutant or the dominant negative PKCalpha ( Lys -- > Arg ), c-Src ( Lys -- > Met ), or STAT1 ( Y701M ) mutants, but not by dominant negative STAT3 ( DN ) mutants
Yang et al., Arterioscler Thromb Vasc Biol 2005 (Myocardial Reperfusion Injury) : Sp1 coimmunoprecipitated with p-S727 Stat3 during H-R, and Sp1 or Stat3alpha interfering RNA markedly reduced ICAM-1 mRNA expression
Wung et al., J Biomed Sci 2005 : ECs transfected with the dominant negative mutant of Stat3 ( Stat3F ) demonstrated that Stat3 was required for IL-6 induced ICAM-1 gene expression
Kim et al., Exp Mol Med 2006 (Encephalitis) : Anti-inflammatory effects of 8-hydroxydeoxyguanosine in LPS induced microglia activation : suppression of STAT3 mediated intercellular adhesion molecule-1 expression ... Evidently, LPS modulates STAT3 dependent ICAM-1 induction through TLR4 mdiated cellular responses