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EZH2 — RASA1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: RASA1 — EZH2 (direct interaction, two hybrid) Vinayagam et al., Science signaling 2011
• IRef Intact Interaction: RASA1 — EZH2 (physical association, two hybrid) Vinayagam et al., Science signaling 2011

Text-mined interactions from Literome

Banerjee et al., Oncogene 2011 (Carcinoma, Squamous Cell...) : By employing an integrative approach, we demonstrate polycomb mediated repression of rap1GAP that involves Enhancer of Zeste Homolog 2 (EZH2) , a histone methyltransferase in head and neck cancers ... EZH2 represses rap1GAP by facilitating the trimethylation of histone 3 at lysine 27, a mark of gene repression, and also hypermethylation of rap1GAP promoter
Banerjee et al., Small GTPases 2012 (Carcinoma, Squamous Cell...) : This microRNA controlled activation of Rap1, via EZH2 mediated silencing of Rap1GAP , is a novel mechanism of Rap1 regulation