Roca et al., Neoplasia (New York, N.Y.) 2009
(Prostatic Neoplasms) :
The CCL2 mediated AMPK regulation decreased raptor phosphorylation ( Ser ( 792 ) ) resulting in hyperactivation of mTORC1 ... By using Akt-specific inhibitor X, it was shown that Akt inactivation did not cause an increase in AMPK phosphorylation in CCL2 stimulated cells, suggesting that CCL2 mediated negative regulation of AMPK is independent of Akt
Declèves et al., J Am Soc Nephrol 2011
(Albuminuria...) :
In vitro, AMPK activation completely inhibited the induction of MCP-1 by palmitic acid in mesangial cells