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LRRC59 — PCNA
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Pillonel et al., Pest Manag Sci 2005
:
A significant correlation was observed between the Neurospora growth inhibition and the intrinsic activity of type A compounds on the
cyclin dependent protein kinase
p34 ( CDC2 ) of starfish, suggesting that the target of phenylaminopyrimidines in fungi is a cyclin dependent protein kinase (CDK)
Meijer et al., EMBO J 1991
:
Several observations point to an extremely close association between accumulation of unphosphorylated cyclin and p34cdc2 tyrosine phosphorylation : ( i ) both events coincide perfectly during the G2 phase ; ( ii ) both tyrosine phosphorylated
p34cdc2 and cyclin are not immunoprecipitated by anti-PSTAIR antibodies ; ( iii ) accumulation of unphosphorylated
cyclin by aphidicolin treatment of the cells,
triggers a dramatic accumulation of tyrosine phosphorylated p34cdc2 ; and ( iv ) inhibition of cyclin synthesis by emetine inhibits p34cdc2 tyrosine phosphorylation without affecting the p34cdc2 concentration
Fellous et al., Int J Dev Biol 1994
:
However,
cyclin was not
necessary for the binding of
p34cdc2 to microtubules since p34cdc2 from activated eggs, where cyclin was missing, still copurified with microtubules
Krucher et al., J Neurobiol 1994
:
Rhythmic cell division is
regulated by periodic synthesis and degradation of a protein, cyclin, and periodic tyrosine phosphorylation of a
cyclin dependent kinase (cdk) ,
p34cdc2