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MPO — NA

Text-mined interactions from Literome

Cuzzocrea et al., Cardiovasc Res 2000 (Reperfusion Injury) : NAC also attenuated the ileum injury ( histology ) as well as the increase in the tissue levels of myeloperoxidase (MPO) and malondialdehyde ( MDA ) caused by SAO shock in the ileum
Yildirim et al., Pulm Pharmacol Ther 2005 (Disease Models, Animal...) : Erdosteine and NAC significantly reduced depletion of glutathione peroxidase, and prevented increases in myeloperoxidase activities, nitric oxide, and malondialdehyde levels in lung tissue produced by bleomycin
Demiralay et al., Toxicology 2006 : Erdosteine, NAC , and vitamin E significantly reduced the increases in TNF-alpha staining and lung MPO activity
Demiralay et al., Hum Exp Toxicol 2007 : NAC and vitamin E significantly reduced the increases in the local production of TNF-alpha and VEGF, and perivascular MPO activity
Vasu et al., Free radical research 2011 (Cystic Fibrosis...) : Ex vivo studies revealed that GSH and NAC effectively scavenged N-chloramines in sputum and inhibited sputum MPO activity with potency exquisitely dependent upon MPO activity levels ... Detailed kinetic analyses revealed that NAC and GSH inhibit MPO by distinct mechanisms