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IL2 — TF
Text-mined interactions from Literome
Woodward et al., Transplantation 1999
:
Transferrin receptor (TfR) expression
follows the induction of
interleukin 2 receptor (IL-2R) expression in a sequence that is necessary to initiate cell proliferation in quiescent T lymphocytes
Huleihel et al., Am J Reprod Immunol 2002
:
In the present study we examined the capacity of interleukin-1 (IL-1) alpha, beta,
interleukin-1 receptor antagonist ( IL-1ra ) and follicle stimulating hormone ( FSH ) to
induce transferrin secretion by Sertoli cells under in vitro conditions
Tang et al., Kidney Int 2002
(Nephritis, Interstitial...) :
Transferrin up-regulated monocyte chemoattractant peptide-1,
interleukin-8 , and macrophage migration inhibitory factor expression in a time- and dose dependent fashion, but had no effect on RANTES expression by PTEC
Rigby et al., Cell Immunol 1990
:
Exogenous
IL-2 did not
increase either IFN-gamma production or
transferrin receptor (TfR) expression in the presence of calcitriol despite increases in cell entry into late G1 and proliferation
Loertscher et al., Transplantation 1989
:
Hence, CD4 positive T cells are the direct target of the suppressor cells, while inhibition of
transferrin and interleukin-2 receptor expression on CD8 positive T cells
results from reduced levels of
interleukin-2 in suppressor cell regulated cultures
Neckers et al., Proc Natl Acad Sci U S A 1983
:
Transferrin receptor induction in mitogen stimulated human T lymphocytes is required for DNA synthesis and cell division and is
regulated by
interleukin 2
Peckham et al., J Clin Immunol 1993
:
However, SAC +
IL-2 induced
transferrin receptors normally in low-responders, showing that some early activation steps occur in these cells