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CCL2 — PTX4

Text-mined interactions from Literome

Chen et al., J Pharmacol Exp Ther 2004 : These data indicate that TNF-alpha stimulated CCL2/MCP-1 production in rat VSMCs is dually regulated by activator protein-1 (AP-1) and NF-kappaB pathways, and inhibition of type III phosphodiesterase contributes substantially to the suppressive effect of PTX on CCL2/MCP-1 production via down-regulation of AP-1 and NF-kappaB signals
Szajnik et al., Oncogene 2009 (Carcinoma...) : In MyD88 ( + ) SCOV3 cells, LPS or PTX binding to TLR4 induced IRAK4 activation and cJun phosphorylation, activated the NF-kappaB pathway and promoted interleukin (IL)-8, IL-6, vascular endothelial growth factor and monocyte chemotactic protein-1 production and resistance to drug induced apoptosis