◀ Back to BDNF
BDNF — EPO
Text-mined interactions from Literome
Viviani et al., J Neurochem 2005
:
These data demonstrate that
erythropoietin activates the CREB transcription pathway and
increases BDNF expression and production, which contributes to erythropoietin mediated neuroprotection
Zhang et al., J Neurosci Res 2006
(Brain Ischemia...) :
EPO also
enhanced the CA1 level of
brain derived neurotrophic factor
Sönmez et al., Surg Neurol 2007
(Spinal Cord Ischemia) :
Recent studies have suggested that
EPO activates the CREB transcription pathway and
increases BDNF expression and production, which contributes to EPO mediated neuroprotection
Girgenti et al., Biol Psychiatry 2009
(Disease Models, Animal...) :
Gene expression profiles revealed that
EPO induces the expression of neurotrophic genes such as
brain derived neurotrophic factor , VGF ( nonacronymic ), and neuritin
Wu et al., Neurobiol Dis 2010
:
Erythropoietin and sonic hedgehog
mediate the neuroprotective effects of
brain derived neurotrophic factor against mitochondrial inhibition ... We found that
BDNF induced
EPO expression at both mRNA and protein levels
Hu et al., Front Biosci (Elite Ed) 2011
(Diabetes Mellitus, Experimental...) :
The results showed that intravitreal
EPO ameliorated the up-regulation of GFAP and vimentin in the diabetic retina evaluated by immunofluorescence and Western blotting ; but
up-regulated BDNF and CNTF expressions, quantified by real-time PCR and ELISA, in the 24-week diabetic rat retinas