Morissette et al., Am J Physiol Cell Physiol 2009
(Hypertrophy) :
Adenoviral overexpression of myostatin attenuated the insulin-like growth factor-I (IGF-I) mediated increase in myotube diameter, as well as IGF-I stimulated Akt phosphorylation ... Inhibition of myostatin by overexpression of the NH ( 2 ) -terminal portion of myostatin was sufficient to increase myotube diameter and Akt phosphorylation
Verzola et al., Kidney Int 2011
(Chronic Disease...) :
Multivariate analysis models showed that phospho-Akt and IL-6 contributed individually and significantly to the prediction of apoptosis and myostatin gene expression, respectively