Gene interactions and pathways from curated databases and text-mining

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ADIPOQ — AKT1

Text-mined interactions from Literome

Ouchi et al., J Biol Chem 2004 (Neovascularization, Pathologic) : Adiponectin promoted the phosphorylation of AMP activated protein kinase (AMPK), protein kinase Akt/protein kinase B, and endothelial nitric oxide synthesis ( eNOS ) in HUVECs
Ogunwobi et al., Mol Cell Endocrinol 2008 (Adenocarcinoma...) : Adiponectin inhibited leptin induced Akt phosphorylation ; this action was sensitive to okadaic acid but not to Compound C. Adiponectin deficiency may contribute to the promotion of OAC in obesity
Wijesekara et al., J Biol Chem 2010 : Adiponectin induced ERK and Akt phosphorylation protects against pancreatic beta cell apoptosis and increases insulin gene expression and secretion
Sánchez-Gurmaches et al., J Exp Biol 2012 : Adiponectin activates Akt in rainbow trout myotubes, which may lead to an increase in fatty acid uptake and oxidation