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ABL1 — PTPN11
Text-mined interactions from Literome
Kusano et al., Endothelium : journal of endothelial cell research 2008
:
To see if tyrosine kinases other than Src are also capable of phosphorylating PZR, the authors cotransfected HEK293 cells with PZR and one of several tyrosine kinases and found that c-Src, c-Fyn, c-Lyn, Csk, and
c-Abl , but not c-Fes, phosphorylated PZR and
increased PZR/SHP-2 interaction
Rubbi et al., Science signaling 2011
(Leukemia) :
We observed
Bcr-Abl mediated phosphorylation of the phosphatase
Shp2 ( Ptpn11 ), and this may contribute to the suppression of these negative feedback mechanisms to promote Bcr-Abl activated SFK signaling