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FOS — TLR8
Text-mined interactions from Literome
Wang et al., Nat Immunol 2006
:
Tumor necrosis factor receptor associated factor 6 ( TRAF6 ) is critical for mediating
Toll-like receptor ( TLR ) -interleukin 1 receptor (IL-1R) signaling and subsequent
activation of NF-kappaB and
AP-1 , transcriptional activators of innate immunity
Hu et al., J Leukoc Biol 2007
:
IFN-gamma suppression of
TLR induced activation of
AP-1 and downstream target genes challenges current concepts about the inflammatory role of AP-1 proteins in macrophage activation and is consistent with a role for AP-1 in the generation of noninflammatory osteoclasts
Wen et al., J Exp Med 2010
(Peritonitis...) :
Rac1 activation is accompanied by JNK ( c-Jun N-terminal kinase ) and NF-?B activation, culminating in
TLR induced binding of NF-?B and
AP-1 to the promoters of inflammatory cytokines