Gene interactions and pathways from curated databases and text-mining

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IL8 — PDGFB

Text-mined interactions from Literome

Wondergem et al., Atherosclerosis 2004 : Compared to cultures exposed to injury alone, radiation induced significant ( P < 0.05 ) increases in mRNA levels of IL-8 ( 1.35 +/- 0.10-fold increase at 4h ), FGF-2 ( 1.62 +/- 0.10-fold at 4h ; 1.76 +/- 0.33-fold at 24h ) and IL-1beta ( 2.76 +/- 0.40-fold at 24h ), whereas mRNA levels of TGF-beta1, PDGF-A and PDGF-B increased about 1.2-fold
Masamune et al., Biochem Pharmacol 2005 : Ellagic acid inhibited platelet derived growth factor (PDGF)-BB induced proliferation and migration, interleukin (IL)-1beta- and tumor necrosis factor (TNF)-alpha induced monocyte chemoattractant protein-1 production, and expression of alpha-smooth muscle actin and collagen genes
van Steensel et al., Invest Ophthalmol Vis Sci 2010 (Graves Ophthalmopathy) : IL-6, IL-8 , CCL2, CCL5, and CCL7 production by orbital fibroblasts was increased by PDGF-BB stimulation, whereas IL-16, IL-1beta, and TNF-alpha production was not affected
Zhang et al., J Dermatol 1995 (Carcinoma, Squamous Cell) : Prostaglandin E1 slightly inhibited PDGF-AB production, transforming growth factor beta 1 promoted PDGF-AB production and interferon-gamma, interleukin-1 alpha, and tumor necrosis factor-alpha failed to exert any influence at all