Gene interactions and pathways from curated databases and text-mining

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IGF1R — MYLIP

Text-mined interactions from Literome

Lu et al., Cardiovasc Res 2010 (Diabetes Mellitus, Type 2...) : Using in silico miRNA target prediction programs, we prioritized candidate miR-223 target genes, but observed no effect of miR-223 on myocyte enhancer factor 2c or insulin-like growth factor 1 receptor , and an unexpected miR-223 induced increase in nuclear factor IA
Huang et al., PloS one 2011 : Overexpression of miR-133 in C2C12 cells significantly suppressed IGF-1R expression at the posttranscriptional level
Guo et al., Oncogene 2013 (Colorectal Neoplasms...) : In this report, we demonstrate that downregulation of microRNA-497 (miR-497) as a result of DNA copy number reduction is involved in upregulation of IGF1-R in CRC cells ... However, only overexpression of miR-497 led to suppression of the IGF1-R 3'UTR activity and downregulation of the endogenous IGF1-R protein in CRC cells
Song et al., Arch Biochem Biophys 2012 (Neointima) : Overexpression of miR-223 or miR-153 down-regulated IGF-1R expression and activity in VSMCs under stretch stress
Gilam et al., Breast Cancer Res Treat 2013 (Breast Neoplasms...) : We identified that disrupting miR-515-5p and igf-1r 3 ' UTR binding by SNP may cause elevated IGF-1R protein levels
Farhana et al., PloS one 2013 : Upregulation of miR-150* and miR-630 Induces Apoptosis in Pancreatic Cancer Cells by Targeting IGF-1R