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HTR1A — HTR1B

Pathways - manually collected, often from reviews:

• Reactome Reaction: HTR1A → HTR1B (reaction) Lerea et al., Neuron 1989, Van Dop et al., Nucleic Acids Res 1989, Itoh et al., J Biol Chem 1988, Takami et al., Brain Res Mol Brain Res 1994

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: HTR1A — HTR1B Salim et al., J Biol Chem 2002
• IRef Bind_translation Interaction: HTR1A — HTR1B (coimmunoprecipitation) Salim et al., J Biol Chem 2002
• MIPS CORUM HTR1A-HTR1B complex: HTR1A-HTR1B complex complex (HTR1A-HTR1B) Salim et al., J Biol Chem 2002
• IRef Corum Interaction: HTR1A — HTR1B (association, coimmunoprecipitation) Salim et al., J Biol Chem 2002
• IRef Hprd Interaction: HTR1A — HTR1B (in vivo) Salim et al., J Biol Chem 2002
• IRef Hprd Interaction: HTR1A — HTR1B (in vitro) Salim et al., J Biol Chem 2002
• IRef Intact Interaction: Complex of FGFR1-HTR1A-HTR1A-FGFR1-HTR1B (physical association, bioluminescence resonance energy transfer) Borroto-Escuela et al., Biol Psychiatry 2012*
• IRef Ophid Interaction: HTR1A — HTR1B (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: HTR1A — HTR1B (aggregation, confirmational text mining) Salim et al., J Biol Chem 2002

Text-mined interactions from Literome

Gur et al., Eur J Pharmacol 2002 : This desensitization of post-synaptic 5- HT(1A) receptors in the hypothalamus may be a consequence of increased 5-HT levels induced by desensitization of the presynaptic 5-HT(1B) receptors
Clark et al., Neurosci Lett 1993 (Seizures) : Kindling induced a persistent bilateral increase in 5-HT1A binding in the dentate gyrus, while 5-HT1B receptors increased only in a delayed fashion
Pauwels et al., Naunyn Schmiedebergs Arch Pharmacol 1998 : The differential regulation of 5-HT1A and 5-HT1B/D agonist responses by GDP suggests that different G-protein subtypes are involved upon 5-HT1A receptor activation by 5-HT1A and 5-HT1B/D agonists