Gene interactions and pathways from curated databases and text-mining

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FOXP3 — IL15

Text-mined interactions from Literome

Ahmadzadeh et al., J Immunother 2007 (Melanoma...) : IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells
Bayer et al., J Immunol 2008 : The present study was undertaken to determine whether the gammac-cytokines IL-7 or IL-15 normally contribute to expression of Foxp3 and Treg cell production
Wuest et al., J Leukoc Biol 2008 : We observed that IL-7 and IL-15 induce STAT5 phosphorylation and up-regulation of FoxP3 in Tregs
Chaput et al., Gut 2009 (Adenocarcinoma...) : Finally, interleukin 6 and TGF beta 1 synergistically induced the generation of CD8 ( + ) CD25 ( + ) Foxp3 ( + ) T cells ex vivo