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BCL6 — CDK1
Text-mined interactions from Literome
Schmitt et al., Oncogene 2007
:
Bcl-xL potently
inhibits cdk1 ( cdc2 ) kinase activity, which is reversible by a synthetic peptide between the 41st amino acid and 60th amino acid surrounding of the Thr47 and Ser62 phosphorylation sites, and Asn52 deamidation site, within the flexible loop domain of bcl-xL
Ibrado et al., Leukemia 1998
:
These findings indicate that
Bcl-xL overexpression does not
affect Taxol induced
CDK1 activity leading to G2/M transition, which temporally precedes the cytosolic cyt c-mediated cleavage and activity of caspase-3 and apoptosis