Gene interactions and pathways from curated databases and text-mining

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LANCL1 — TLR4

Text-mined interactions from Literome

Jackson et al., Int J Cancer 2008 (Melanoma...) : Melanoma-lysate markedly suppressed TLR4 dependent IL-12p40 and p70 production
Matsushita et al., Nature 2009 (Anemia...) : Macrophages from Zc3h12a ( -/- ) mice showed highly increased production of interleukin (IL)-6 and IL-12p40 ( also known as IL12b ), but not TNF, in response to TLR ligands
McBerry et al., J Immunol 2012 (Disease Models, Animal...) : p38 MAPK activation and IL-12p70 production was more robust from TFF2 ( -/- ) CD8+ DC compared with WT CD8+ DC and treatment of WT DC with rTFF2 suppressed TLR induced IL-12/23p40 production