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HGF — SP1
Text-mined interactions from Literome
Friedrich et al., J Biol Chem 2002
:
The crystal structure of the MT-SP1 complex with bovine pancreatic trypsin inhibitor serves as a model for
hepatocyte growth factor activator inhibitor 1, the physiological
inhibitor of
MT-SP1 , and suggests determinants for the substrate specificity
Reisinger et al., J Cell Sci 2003
(Neovascularization, Pathologic) :
Together, our results elucidate a critical pathway of paracrine amplification of angiogenesis, suggesting that
HGF/SF induced
Sp1 phosphorylation may activate VEGF/VPF promoter activity that requires the contribution of distinct signaling molecules
Tan et al., J Am Soc Nephrol 2007
(MAP Kinase Signaling System) :
Chromatin immunoprecipitation assay revealed that activated CREB and
Sp1 bound to their cognate cis acting elements in SnoN promoter in
response to
HGF stimulation