Gene interactions and pathways from curated databases and text-mining

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ETS1 — SP1

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Kavurma et al., J Biol Chem 2002 (Arteriosclerosis) : Conversely, Ets-1 activation of the promoter was blocked by an Sp1 mutant bearing the DNA binding domain
Liu et al., Eur J Biochem 2003 : Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3
Sato et al., J Biol Chem 2007 : To solve this problem, we examined the transcriptional regulation of the human Sp1 gene by Ets-1 and found that the gene expression and promoter activity of Sp1 are regulated by Ets-1 in cancer cells