Gene interactions and pathways from curated databases and text-mining

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P2RY12 — SELP

Text-mined interactions from Literome

Evans et al., Circulation 2009 (Atherosclerosis...) : The P2Y(12) receptor ( P2Y(12) ) plays a central role in amplifying platelet aggregation, dense granule and alpha-granule secretion, P-selectin expression, microparticle formation, and procoagulant membrane changes, regardless of the activating stimulus
Judge et al., Thromb Haemost 2010 (Coronary Thrombosis) : A P2Y12 receptor blockade of 60-80 % resulted in strong inhibition of final PA response, P-selectin expression, microparticle formation and vasodilator stimulated phosphoprotein ( VASP )
Li et al., Arterioscler Thromb Vasc Biol 2012 (Atherosclerosis) : In vitro studies showed that platelet P2Y12 deficiency suppressed platelet factor 4 secretion and P-selectin expression