Gene interactions and pathways from curated databases and text-mining

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PLAU — RHOA

Text-mined interactions from Literome

Jo et al., J Biol Chem 2002 : uPA did not significantly increase the level of GTP bound RhoA , suggesting that the constitutive activity of the Rho-Rho kinase pathway may be sufficient to support ERK stimulated cell migration
Kiian et al., Thromb Haemost 2003 : Endogenous RhoA , but not Rac1 or Cdc42, was significantly activated in response to uPA
Kunigal et al., Int J Oncol 2006 (Glioblastoma...) : SPARC induced migration of glioblastoma cell lines via uPA-uPAR signaling and activation of small GTPase RhoA
Graziano et al., PloS one 2011 : uPA induced activation of RhoA , PKCd and PKCe in PMA differentiated U1 cells