Gene interactions and pathways from curated databases and text-mining

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KLF2 — RELA

Text-mined interactions from Literome

Lin et al., Arterioscler Thromb Vasc Biol 2006 : Mechanistically, KLF2 inhibits PAR-1 expression and, as a consequence, thrombin mediated nuclear factor kappaB (NF-kappaB) nuclear accumulation and DNA binding ... Conversely, small interfering RNA mediated knockdown of KLF2 increases PAR-1 expression and thrombin mediated induction of NF-kappaB activation
Das et al., Proc Natl Acad Sci U S A 2006 (Atherosclerosis...) : Mechanistically, KLF2 inhibits the transcriptional activity of both NF-kappaB and activator protein 1, in part by means of recruitment of transcriptional coactivator p300/CBP associated factor
Zahlten et al., J Immunol 2010 (Disease Models, Animal...) : KLF2 dependent downregulation of NF-kappaB activity is partly reversible by overexpression of the histone acetylase p300/CREB binding protein associated factor