Gene interactions and pathways from curated databases and text-mining

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CALM1 — PTK2B

Text-mined interactions from Literome

Heidinger et al., J Neurosci 2002 : Here we show that in cortical neurons, brief selective activation of group I mGluRs with ( S ) -3,5-dihydroxy-phenylglycine ( DHPG ) induced a Ca ( 2+ ) -calmodulin dependent activation of Pyk2/CAKbeta and the Src-family kinases Src and Fyn that was independent of protein kinase C ( PKC )
Kohno et al., Biochem J 2008 : Protein-tyrosine kinase CAKbeta/PYK2 is activated by binding Ca2+/calmodulin to FERM F2 alpha2 helix and thus forming its dimer
Tsao et al., J Cell Physiol 2012 : Src activation and calcium/calcium activated calmodulin kinase II ( CaMKII ) were involved in IFN-a induced phosphorylation of proline-rich tyrosine kinase 2 (Pyk2) ( Tyr402 ) and GSK-3ß ( Tyr216 ), which regulated 5-HT uptake