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MAPK7 — PML

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: MAPK7 — PML (physical association, affinity chromatography technology) Yang et al., Cancer Cell 2010*
• IRef Intact Interaction: Complex of PML-MAPK7 (colocalization, fluorescence microscopy) Yang et al., Cancer Cell 2010*
• IRef Intact Interaction: PML — MAPK7 (physical association, anti bait coimmunoprecipitation) Yang et al., Cancer Cell 2010*
• IRef Intact Interaction: PML — MAPK7 (phosphorylation reaction, protein kinase assay) Yang et al., Cancer Cell 2010*

Text-mined interactions from Literome

Son et al., Cancer Lett 2007 (Breast Neoplasms) : We concluded that PML and all-trans-retinoic acid cause cell death by different pathways : PML activates ERK1/2, p38 MAPK , and p21 ; arrests the cell cycle ; and later causes cell death ; and all-trans-retinoic acid activates proteasome function, caspase cleavage, and apoptosis
Yang et al., Oncogene 2013 : We found that activated big MAP kinase 1 (BMK1) preferentially associates with PML isoform IV and disrupts PML-MDM2 interaction