Gene interactions and pathways from curated databases and text-mining

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MYC — TFRC

Text-mined interactions from Literome

O'Donnell et al., Mol Cell Biol 2006 (Lymphoma, B-Cell) : Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis ... Using in vitro and in vivo models of B-cell lymphoma, we show that TFRC1 expression is activated by c-Myc
Okazaki et al., Cancer Res 2010 (Colonic Neoplasms) : Luciferase reporter analysis and chromatin immunoprecipitation experiments suggested that the clock controlled gene c-MYC rhythmically activated the transcription of the TfR1 gene
Holland et al., Nat Med 2012 (Prostatic Intraepithelial Neoplasia...) : The use of ( 89 ) Zr-transferrin produces high-contrast PET images that quantitatively reflect treatment induced changes in MYC regulated TFRC expression in a MYC-driven prostate cancer xenograft model