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CEBPB — IL10
Text-mined interactions from Literome
Liu et al., J Immunol 2003
:
In this study, we determined that, in addition to Sp1,
C/EBPbeta and delta were also
involved in LPS induced gene expression of
IL-10 ... These results suggested that the interaction between Sp1 and
C/EBPbeta and delta induced by LPS cooperatively
activated expression of the
IL-10 gene
Tanaka et al., Am J Respir Cell Mol Biol 2005
:
Interleukin-10 induces inhibitory
C/EBPbeta through STAT-3 and represses HIV-1 transcription in macrophages ... In contrast, in undifferentiated THP-1 monocytes,
IL-10 did not inhibit HIV-1 replication or
induce C/EBPbeta ... Differentiation induced post-transcriptional regulation is required to produce inhibitory
C/EBPbeta in
response to
IL-10
Csóka et al., Blood 2007
:
A2A adenosine receptors and
C/EBPbeta are crucially
required for
IL-10 production by macrophages exposed to Escherichia coli
Qin et al., J Leukoc Biol 2010
:
Bioinformatics analysis identified KSHV miRNA binding sites formiR-K12-3 and miR-K12-7 within the 3'UTR of the basic region/leucine zipper motif transcription factor
C/EBPbeta , a known
regulator of IL-6 and
IL-10 transcriptional activation.Subsequent immunoblot analyses revealed that miR-K12-3 and miR-K12-7 preferentially reduce expression of C/EBPbeta p20 ( LIP ), an isoform of C/EBPbeta known to function as a negative transcription regulator