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CCR5 — IL10

Text-mined interactions from Literome

Houle et al., Inflammation 1999 : Pretreatment of monocytes with actinomycin D prevented the IL-10 induced effect, suggesting a transcriptional mechanism for CCR5 up-regulation by IL-10 ... Protein expression of CCR5 was also enhanced by IL-10 , as indicated by a 3-fold increase in anti-CCR5 antibody labeling of monocytes treated for 20 h with IL-10
Biasin et al., J Infect Dis 2000 : However, interleukin (IL)-6 , IL-10, IL-12, interferon (IFN)-gamma, and tumor necrosis factor (TNF)-alpha and -beta mRNA were elevated in PBMC and cervical mucosa biopsy specimens of ESN and HIV infected women ; CCR5 and CXCR4 mRNA were augmented in cervical mucosa biopsy specimens, but not in PBMC, of ESN and HIV infected women ; HIV-specific IFN-gamma secreting cells were detected in vaginal washes of ESN and HIV infected women ; and phenotypic alterations were present in PBMC of ESN women ... However, interleukin (IL)-6, IL-10 , IL-12, interferon (IFN)-gamma, and tumor necrosis factor (TNF)-alpha and -beta mRNA were elevated in PBMC and cervical mucosa biopsy specimens of ESN and HIV infected women ; CCR5 and CXCR4 mRNA were augmented in cervical mucosa biopsy specimens, but not in PBMC, of ESN and HIV infected women ; HIV-specific IFN-gamma secreting cells were detected in vaginal washes of ESN and HIV infected women ; and phenotypic alterations were present in PBMC of ESN women
Dieu-Nosjean et al., J Immunol 2001 : The effect of IL-10 was reversible and upon IL-10 withdrawn, CCR6 was lost concomitantly to final LC differentiation
Makuta et al., Biol Pharm Bull 2003 : Interleukin-10 induced CCR5 expression in macrophage like HL-60 cells : involvement of Erk1/2 and STAT-3 ... IL-10 induced significant expression of CCR5 protein and CCR5 mRNA in these cells ... The induction of CCR5 by IL-10 was inhibited by a MEK-1 inhibitor, PD98059
Fernandez et al., J Immunol 2004 : However, the addition of TLR ligands inhibited IL-10 induced expression of CCR1 and CCR5
Bosco et al., Cell Immunol 2004 : CCR5 upregulation by IL-10 , LPS, and IL-4 was also antagonized by hypoxia
Takei et al., Pathobiology 2005 : These results indicate that GL inhibits R5 HIV replication in fresh PBM/MA through the inhibiting CCR5 expression mediated by CCL2 or IL-10
Zhang et al., Arthritis Rheum 2005 (Arthritis, Rheumatoid) : In contrast, interleukin-12 stimulation induced the up-regulation of CCR5 and a shift in the in vivo homing pattern away from the lymph nodes toward the inflamed synovium
Jiang et al., Chin Med J (Engl) 2009 (Embryo Loss) : Expression of chemokine receptors CCR3, CCR5 and CXCR3 on CD4 ( + ) T cells in CBA/JxDBA/2 mouse model, selectively induced by IL-4 and IL-10 , regulates the embryo resorption rate ... This study aimed to observe whether IL-4 and IL-10 may regulate the expression of chemokine receptors CCR3, CCR5 and CXCR3 on CD4 ( + ) T cells in CBA/JxDBA/2 mouse model and to explore the role of CCR3, CCR5, CXCR3 in immune tolerance in pregnancy
Tian et al., Invest Ophthalmol Vis Sci 2012 (Behcet Syndrome) : VitD3 was able to inhibit the gene expression of RORC, IL-17, IL-23R, CCR6 , and Th1 cell differentiation, but upregulated IL-10 expression
Sozzani et al., J Exp Med 1998 (HIV Infections) : Interleukin 10 increases CCR5 expression and HIV infection in human monocytes ... The immunosuppressive and antiinflammatory cytokine interleukin (IL) 10 selectively upregulates the expression of the CC chemokine receptors CCR5 , 2, and 1 in human monocytes by prolonging their mRNA half-life