◀ Back to IDO1

IDO1 — MSC

Text-mined interactions from Literome

Popp et al., Transpl Immunol 2008 : This tolerogenic effect of MSC is at least partially mediated by the expression of indoleamine 2,3-dioxygenase (IDO) , demonstrated by the fact that blocking of IDO with 1-methyl tryptophan ( 1-MT ) abrogates graft acceptance
Tatara et al., Cytotherapy 2011 : Under Th17 conditions, MSC did not produce NO, and inhibitors of indoleamine-2,3-dioxygenase (IDO) and prostaglandin E ( 2 ) ( PGE2 ) both restored MSC suppression of differentiation, suggesting that MSC suppress Th17 differentiation at least in part through PGE2 and IDO
François et al., Cytotherapy 2012 : Human mesenchymal stromal cells (MSC) can suppress T-cell activation in vitro in an indoleamine 2,3-dioxygenase (IDO) dependent manner