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FOS — HGF

Text-mined interactions from Literome

Rahmani et al., J Hepatol 1999 (Liver Neoplasms, Experimental) : We have investigated whether hepatocyte growth factor (HGF) induces differential AP-1 responses in normal and transformed rat hepatocytes, the 7777 cells ... HGF induced AP-1 activation leads to the formation of distinct dimers with different functional capacities in normal and transformed hepatocytes
Gao et al., Hepatology 1999 : HGF alone induced moderate levels of c-Jun-N-terminal kinase (JNK) and p44/p42 mitogen activated protein kinase ( MAPK ), resulting in moderate levels of AP-1-DNA binding activity ... LPS may contribute to hepatocyte replication by potentiating the effect of HGF on the activation of both AP-1-DNA binding and transcriptional activity
Seol et al., Oncogene 2000 (Carcinoma, Hepatocellular) : Stimulation of Hepa 1-6 cells with HGF resulted in a rapid and dramatic enhancement of the AP-1 binding activity as well as an overall increase in the level of AP-1 protein
Takeuchi et al., J Biol Chem 2001 : Activation of phosphatidylinositol-3'-OH kinase and FKBP12-rapamycin associated mammalian target of rapamycin ( FRAP/mTOR ) was observed after the treatment with HGF/SF. Pretreatment with an inhibitor of either one, i.e. LY294002 for phosphatidylinositol-3'-OH kinase or rapamycin for FRAP/mTOR, completely inhibited 4E-BP1 phosphorylation and decreased the c-Fos synthesis induced by HGF/SF down to the level found in EGF induced cells
Bianchi et al., Arch Biochem Biophys 2002 (Melanoma, Experimental) : Since in B16-F1 cells HGF increased AP-1 activity and the mRNA expression of various AP-1 subunits, we may conclude that HGF induced transcription of mouse ODC was largely due to triggering of AP-1 pathway
Chen et al., PloS one 2012 : HGF mediated AP-1-luciferase activity and c-Jun binding to the AP-1 element was reduced by c-Met inhibitor, Ly294002, Akt inhibitor, and PP2
Baptist et al., Exp Cell Res 1995 : ( i ) EGF and HGF induced c-Fos accumulation and MAP kinase translocation in variable fractions of the cell population that corresponded to their relative potency as mitogens