Tfelt-Hansen et al., Endocrinology 2004
(Astrocytoma...) :
PTTG induction by EGF receptor (EGFR) ligands could be blocked by the specific EGFR inhibitor, AG1478
Vlotides et al., Mol Endocrinol 2006
(Pituitary Neoplasms) :
EGFR ligands induce PTTG1 and regulate S-phase, mediated by phosphatidylinositol 3 kinase, protein kinase C, and MAPK pathways ... PTTG1 is therefore a target for EGFR mediated paracrine regulation of pituitary cell growth