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CXCL12 — JAK3
Text-mined interactions from Literome
Moriguchi et al., J Biol Chem 2005
:
CXCL12 signaling is
independent of Jak2 and
Jak3 ... We found that the lack of
Jak3 had no effect on
CXCL12 signaling or chemotaxis nor did overexpression of wild-type versions of the kinase
Lee et al., Int J Biochem Cell Biol 2007
(MAP Kinase Signaling System) :
The OSM stimulated expression of SDF-1 in hATSCs was completely abrogated by pretreatment of the cells with U0126, an MEK-specific inhibitor, but not with AG490, a JAK2 inhibitor, or WHI-P131, a JAK3 inhibitor, suggesting that ERK, but not JAK2 and
JAK3 , is
involved in the OSM induced expression of
SDF-1