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CAV1 — CTNNB1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of CAV1-GSK3B-LRP6-CTNNB1-LRP6-CTNNB1-CAV1-GSK3B (physical association, anti tag coimmunoprecipitation) Yamamoto et al., Dev Cell 2006

Text-mined interactions from Literome

Torres et al., J Cell Sci 2006 : In addition, expression of caveolin-1 inhibited transcriptional activity of a survivin promoter construct in a beta-catenin-Tcf/Lef dependent manner
Yamamoto et al., Dev Cell 2006 : Overall, our data suggest that Wnt-3a triggers the interaction of LRP6 with caveolin and promotes recruitment of Axin to LRP6 phosphorylated by glycogen synthase kinase-3beta and that caveolin thereby inhibits the binding of beta-catenin to Axin
Case et al., J Biol Chem 2008 : The increase of beta-catenin was temporally related to the activation of Akt and subsequent inactivation of GSK3beta, and caveolin-1 was not required for these molecular events
Mo et al., Dev Biol 2010 : Cav-1 overexpression disrupts the nuclear translocation of beta-catenin through the interaction of its scaffolding domain with Cav-1 binding motif of beta-catenin