Kadaja-Saarepuu et al., Oncogene 2008
(Neoplasms) :
However, when both p53 and ARF proteins are present, CD43 overexpression activates p53 and suppresses colony formation due to induction of apoptosis
Molina-Pinelo et al., J Pathol 2011
(Carcinoma, Non-Small-Cell Lung...) :
However, in the absence of p53 , reduced levels of Spn increase the tumourigenic properties of cells