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ITGB1 — TNF

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: Complex of ITGA5-ITGB1 → TNF (increases)
  Evidence: alpha2beta1 is upregulated by VEGF, alphaVbeta3 and alpha5beta1 are not, but instead are induced by bFGF, TNF and other angiogenic cytokines

Text-mined interactions from Literome

Freysdottir et al., Clin Exp Immunol 1999 (Behcet Syndrome...) : Furthermore, in BD a significantly increased proportion of the gammadelta T cell population expressed CD69 and high levels of CD29 and were induced to produce IFN-gamma and TNF-alpha compared with healthy controls
Montesano et al., J Cell Sci 2005 : Collectively, these results demonstrate an essential role for MMPs and alpha2beta1 integrin in the invasive response of 31EG4-2A4 cells to TNF-alpha
Ishii et al., J Oral Pathol Med 1990 : TNF-alpha , interleukin-4 (IL-4), and transforming growth factor beta ( TGF-beta ) suppressed CD29 expression, while other cytokines, including interleukin-3 and granulocyte-macrophage colony stimulating factor, were without effect
Lee et al., Chem Biol Interact 2011 (Leukemia, Monocytic, Acute) : Rh1 and CK dampened induction of counter-receptors, a4/ß1 integrin VLA-4 and aL/ß2 integrin LFA-1 in TNF-a treated THP-1 cells
Xie et al., J Biol Chem 1998 : Our results suggest that TNF-alpha may regulate macrophage differentiation and critical matrix degrading activities of myeloid progenitor cells in an autocrine manner by augmenting surface levels of the alpha5 beta1 integrin , thus promoting interactions with the extracellular matrix, a key event for maturation and migration of these cells during inflammation