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ISG20 — STAT1

Text-mined interactions from Literome

Plumlee et al., Virology journal 2005 : Stat1 and Stat2 combine with the IRF-9 protein to form the transcription factor interferon stimulated gene factor 3 ( ISGF-3 ), which binds to the interferon stimulated response element ( ISRE ), and induces transcription of IFN-alpha induced genes ( ISG )
Zhang et al., Biochim Biophys Acta 2006 (Carcinoma, Hepatocellular...) : Hyper activated IRF-1 and STAT1 contribute to enhanced interferon stimulated gene ( ISG ) expression by interferon alpha and gamma co-treatment in human hepatoma cells
Byrnes-Blake et al., J Interferon Cytokine Res 2012 (Hepatitis C, Chronic) : However, STAT1 phosphorylation, MHC class 1 upregulation, and ISG induction in leukocytes only occurred with IFNa
Kumthip et al., J Virol 2012 : We propose a model in which the binding of the C-terminal region of NS5A to STAT1 leads to decreased levels of P-STAT1, ISRE signaling, and ISG transcription and, ultimately, to preferential GT1 resistance to IFN treatment