Gene interactions and pathways from curated databases and text-mining

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AKT2 — RASA1

Text-mined interactions from Literome

Yue et al., J Biol Chem 2004 : Overexpression of RasGAP or a mutant lacking the GTPase activating domain ( nGAP ) enhanced phosphorylation and activity of Akt , which was dependent on the upstream integrin linked kinase ... To determine the role of RasGAP in receptor mediated activation of Akt , we used short hairpin RNA interference to knock out endogenous RasGAP expression
Chavez et al., J Biol Chem 2008 : These results indicate that endogenous Tbc1d1 does not participate in insulin regulated GLUT4 translocation in adipocytes and suggest that the GAP activity of Tbc1d1 is not suppressed by Akt phosphorylation
Bouzakri et al., Diabetes 2008 (Diabetes Mellitus, Type 2) : Rab GTPase activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells