◀ Back to RAC3

HSPG2 — RAC3

Text-mined interactions from Literome

Kanazawa et al., J Biol Chem 2002 : Furthermore, dominant negative forms of PLC-gamma completely suppressed PDGF induced Iba1 dependent membrane ruffling and Rac activation ... These results indicate the existence of a novel signaling pathway where PLC-gamma activates Rac in a manner dependent on Iba1
Bourdon et al., Methods Enzymol 2006 : This method is readily applied to quantify activation of PLC by receptors and G proteins, and we illustrate here the selective activation of PLC-beta2 by Rac but not by Rho GTPases and the selective activation of PLC-epsilon by Rho but not Rac GTPases
Choi et al., Cell Signal 2007 : Interestingly, PLC-gamma1 potentiated the activations of Rac , thus integrin induced lamellipodia formation was up-regulated
Everett et al., J Biol Chem 2009 : Analysis of PLC gamma 1 and PLC gamma 2 with point mutations of this residue showed that removal of the negative charge enhanced PLC activity in response to EGF stimulation or activation by Rac
Notcovich et al., Exp Cell Res 2010 : Our results reveal that functional coupling of the H1R to Gq-PLC leads to the activation of RhoA and Rac small GTPases and suggest distinct roles for Rho GTPases in the control of cell proliferation by histamine