Gene interactions and pathways from curated databases and text-mining

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PI3 — SLCO6A1

Text-mined interactions from Literome

Chuang et al., J Biol Chem 1994 : Thus, microinjection of GST-fusion proteins of either p85 or GRB2 inhibited IRS-1 dependent activation of mitogen activated protein ( MAP ) and S6 kinases and oocyte maturation, although only the GST-SH2 of p85 reduced insulin stimulated PI 3-kinase activation
Zheng et al., J Biol Chem 1994 : In addition, PI 3-kinase activity immunoprecipitated from cell lysates with anti-p85 antibody was stimulated 2-4-fold by GST-Cdc42-GTP gamma S. Similar interactions were observed between p85 and GST-Rac1-GTP gamma S but not between p85 and GST-RhoA-GTP gamma S